NINGBO ZHENGGUANG RESIN CO., LTD.

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86-571-86372141

zg@chinaresin.com

Ningbo Zhengguang Resin Co.,Ltd.
STOCK CODE: 301092

 

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Chromatographic media
 

Thoth Affinity Series ThothTM AU50,ThothTM A50
Alkali-resistant agarose-based Protein A chromatography medium

Product Description
The ThothTM affinity series represents the next generation of agarose-based IgG capture medium, featuring uniform 50 μm beads designed for short residence times, high mechanical strength, and superior binding capacity.
The key features of ThothTM AU50 and ThothTM A50:
1)Customized 50 μm particle size provides higher capture efficiency;
2)Highly cross-linked matrix provides superior pressure-flow characteristics and mechanical stability;
3)Optimized pore structure maintains high dynamic binding capacity even at reduced residence times; 
4)Alkali-resistant protein A ligand with independent intellectual property rights.
Among them, ThothTM AU50 is coupled with a highly alkali-resistant Protein A ligand (tolerant to 0.5-1M NaOH). While ThothTM A50 is coupled with a standard alkali-resistant Protein A ligand (tolerant to 0.1-0.5M NaOH). It provides biopharmaceutical clients with a broader range of options.

Matrix
Matrix High-strength agarose beads
Average Particle Size 50 um
Ligand Alkali-resistant Protein A
Dynamic Binding Capacity (DBC) ~65 mg IgG /mL (2min RT 10% breakthrough)
Alkaline Stability (CIP) 0.5-1.0 M NaOH(ThothTM AU50)
0.1-0.5 M NaOH(ThothTM A50)
Max. Operating Pressure 0.7 Mpa
Product Information
Product Packaging Cat.No.
ThothTM AU50
Uniform High Alkali-resistant
Protein A Affinity Chromatography Medium
25 mL
100 mL
500 mL
1 L
5 L
30 L
TT910231
TT910232
TT910233
TT910234
TT910235
TT910236
ThothTM A50
Uniform Alkali-resistant
Protein A Affinity Chromatography Medium
25 mL
100 mL
500 mL
1 L
5 L
30 L
TT909231
TT909232
TT909233
TT909234
TT909235
TT909236
  •  Figure1: 50 μm uniform high-strength beads
  • Figure2: Dynamic binding capacity of ThothTM A50/AU50 
  • Figure3: Alkaline stability of  ThothTM A50/AU50


MAIN PRODUCT
As a leading ion exchange resin manufacturer in China, Zhengguang is manufacturing an extensive resin series,
and delivering the supporting equipment and EPC project of separation & purification process.

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TEL:86-571-86372141     86-571-86372390
Technical Service:86-571-86372035

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TEL:86-571-86372141/86372390
Techinical Service:86-571-86372035
zg@chinaresin.com
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